4.3mm) underwent roboc-assisted
biopsy. There were no complicaons
and the overall diagnosc yield was
83%. A similar roboc plaorm
(Monarch) developed by Auris
Health has been shown to be able to
reach further out in the lung com-
pared to a convenonal thin bron-
choscope with an idencal outer
diameter in cadavers [4]. Further-
more, Auris Health recently received
FDA approval for the clinical use of
the Monarch system. The unique
features of the roboc plaorms
may be the ability to navigate out
into the distal airways under conn-
uous visualizaon and the ability to
maintain stac posion. These new
roboc plaorms will likely improve
the diagnosc yield but more inter-
esngly enable precise transbron-
chial therapeucs. The future of
guided bronchoscopy is bright, and I
look forward to the innovaons.
Editor-in-Chief
Kazuhiro Yasufuku
References
1. Wang Memoli et al. Chest 2012; 143;
385-93
2. Ost et al. Am J Respir Crit Care Med
2016; 193: 68-77
3. Fielding et al. Chest 2017; 152: Sup-
plement A858
4. Chen et al. Ann Thorac Surg. 2018
Feb 24 [Epub ahead of print]
Surgeons and pulmonologists are
asked to see an increasing number of
paents with pulmonary nodules.
When ssue diagnosis is required,
transthoracic needle aspiraon
(TTNA) has been the standard of care
for the majority of paents. TTNA
has a high yield of 90% which is usu-
ally not limited to the locaon of the
nodule. However, TTNA also has a
pneumothorax rate of about 25%
and as such, may not be suitable for
some paents. Tradional exible
bronchoscopy has a relavely low
yield for the diagnosis of pulmonary
nodules depending on the size and
locaon of the nodule. Newer tech-
nologies to guide exible bronchos-
copy has emerged over the past 10-
20 years as a viable opon when the
bronchoscopist has the experse.
These technologies include virtual
bronchoscopy, electromagnec navi-
gaon bronchoscopy (ENB), radial
probe endobronchial ultrasound (RP-
EBUS) and ultra-thin bronchoscopy.
A meta-analysis published in 2012
looking at the role of guided bron-
choscopy for the evaluaon of pul-
monary nodules showed a pool diag-
nosc yield of 70% which is sll low-
er than TTNA but signicantly higher
than tradional exible bronchosco-
py (1). Perhaps the advantage of
guided bronchoscopy is the low ad-
verse event rate with only 1.5%
chance of pneumothorax. However,
the majority of the publicaons as-
sessed in the meta-analysis were
from expert centers in the world,
data from clinical studies and the
numbers may not reect the real
world. A recent study looking at the
AQuIRE Registry for the diagnosc
yield and complicaons of bronchos-
copy for peripheral lung lesions
showed a slightly dierent result (2).
The overall diagnosc yield of bron-
choscopy was only 53.7%, although
the sensivity for lung cancer was
between 60-74%. Interesngly, unad-
justed for other factors, the diagnos-
c yield was 63.7% when no RP-EBUS
and ENB were used, 57% with RP-
EBUS alone, 38.5% with ENB alone
and 47.1% with ENB and RP-EBUS
combined. Transbronchial needle
aspiraon (TBNA), larger lesion size
and non-upper lobe locaon was as-
sociated with increased diagnosc
yield on mulvariate analysis. Compli-
caons only occurred in 2.2% of pa-
ents. Aer over a decade of experi-
ence with guided bronchoscopy, are
we sll not geng any beer with
transbronchial biopsy of peripheral
lung nodules?
The introducon of robocs has
changed the landscape of minimally
invasive surgery. In parcular, retro-
specve studies published over the
past decade show that roboc sur-
gery for lung cancer has the ad-
vantages of minimally invasive sur-
gery for paents and some ad-
vantages over VATS for the surgeon.
Although data is limited, oncological
outcomes are comparable with those
of VATS and open surgery while
lymph node dissecon may be more
radical. However, the high costs of
purchase, maintenance and consum-
ables are a concern. Nevertheless,
roboc thoracic surgery is widely be-
ing adopted into pracce, especially
in North America. What about ro-
bocs for bronchoscopy?
At least two companies are develop-
ing roboc bronchoscopy plaorms.
A rst in human study was presented
at the Chest 2017 annual meeng
using the Intuive Surgical roboc
assisted bronchoscopy system [3]. 30
paents with small peripheral lung
nodules (mean axial size 12.5 +
Guest Opinion/Editorial
WABIP Newsletter
M A Y 2 0 1 8 V O L U M E 6 , I S S U E 2
EXECUTIVE BOARD
Zsolt Papai MD
Székesfehérvár, Hun-
gary
Chair
Silvia Quadrelli MD
Buenos Aires, Argen-
na
Vice-chair
Hideo Saka MD
Nagoya, Japan
Secretary General
Hojoong Kim MD
Seoul, Korea
Treasurer
Eric Edell MD
Rochester MN, USA
President WCBIP 2018
Quangfa Wang MD
Beijing, China
President WCBIP 2020
Henri Colt MD
Laguna Beach, CA
Immediate Past-chair
STAFF
Michael Mendoza
General Manager
Judy McConnell
Administrator
Kazuhiro Yasufuku
Newsleer Editor-in-
chief
P A G E 2
Future of Guided Bronchoscopy for Transbronchial Biopsy of Peripheral Lung Nodules